STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMK54698.1TIGRFAM: cysE: serine O-acetyltransferase; Pfam: Bacterial transferase hexapeptide (six repeats). (162 aa)    
Predicted Functional Partners:
AMK55282.1
Cysteine synthase A; Pfam: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysK: cysteine synthase A; TIGRFAM: cysKM: cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.983
cysS
cysteinyl-tRNA synthetase; TIGRFAM: cysS: cysteine--tRNA ligase; PRINTS: Cysteinyl-tRNA synthetase signature; Pfam: tRNA synthetases class I (C) catalytic domain; Pfam: DALR domain; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.933
AMK53656.1
L-serine ammonia-lyase; Pfam: Serine dehydratase alpha chain; Pfam: Serine dehydratase beta chain.
     
 0.910
AMK54401.1
Serine acetyltransferase; Pfam: Bacterial transferase hexapeptide (six repeats).
  
  
 
0.907
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.824
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
 0.824
AMK55506.1
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
 0.816
AMK54887.1
'Pfam: Homoserine dehydrogenase, NAD binding domain; Pfam: Homoserine dehydrogenase'.
     
 0.815
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.813
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.810
Your Current Organism:
Faecalibaculum rodentium
NCBI taxonomy Id: 1702221
Other names: Allobaculum sp. Alo17, Erysipelotrichaceae bacterium Alo17, F. rodentium, Faecalibaculum rodentium Chang et al. 2016 emend. Cox et al. 2017, JCM 30274, KCTC 15484, strain ALO17
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