STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP52549.1Uricase (urate oxidase); Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (294 aa)    
Predicted Functional Partners:
AOP52548.1
5-Hydroxyisourate Hydrolase (HIUase); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
  
 0.949
AOP52547.1
2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase.
 
   
 0.929
AOP52542.1
Allantoinase.
 
  
 0.878
AOP52553.1
Hypothetical protein; FIG01194264; Belongs to the HpcH/HpaI aldolase family.
 
     0.844
AOP51796.1
Xanthine permease.
 
  
 0.718
AOP52538.1
Xanthine permease.
 
  
 0.714
AOP52539.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
     0.621
AOP52537.1
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
  
 0.599
AOP51797.1
Guanine deaminase; Hydroxydechloroatrazine ethylaminohydrolase.
 
  
 0.595
AOP52550.1
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.595
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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