STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa)    
Predicted Functional Partners:
AOP52651.1
Protein of unknown function DUF1469.
       0.656
AOP52758.1
Sodium-solute symporter, putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.613
AOP51995.1
Fumarate hydratase class I.
  
  
 0.552
AOP52757.1
Putative membrane protein.
  
    0.549
AOP52615.1
NAD-dependent protein deacetylase of SIR2 family.
   
 0.542
AOP53982.1
Transcriptional regulator.
   
   0.540
AOP52983.1
Enoyl-CoA hydratase [valine degradation].
 
  
 0.534
AOP52061.1
Fatty-acid-CoA ligase FadD7.
 
    0.531
AOP54477.1
DNA polymerase III alpha subunit.
  
  
 0.528
AOP53448.1
Putative transcriptional regulator.
   
 
 0.522
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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