Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOP52692.1Acyl dehydratase; FIG00820637. (167 aa)    
Predicted Functional Partners:
AOP52693.1
Hydroxymethylglutaryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.975
AOP54351.1
Citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.736
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.722
AOP52684.1
Transcriptional regulator, TetR family.
 
   
 0.655
AOP55476.1
Hypothetical protein.
 
     0.627
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.621
AOP55281.1
TesB-like acyl-CoA thioesterase 5.
 
 
 0.620
AOP52682.1
Enoyl-CoA hydratase [isoleucine degradation]; 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase.
  
 0.614
AOP52687.1
Isovaleryl-CoA dehydrogenase.
 
 0.578
msrA
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.553
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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