STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde aminotransferase. (445 aa)    
Predicted Functional Partners:
AOP52768.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.968
hemA
Porphobilinogen deaminase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA); Belongs to the HMBS family.
 
 0.965
AOP52767.1
Uroporphyrinogen-III synthase.
 
  
 0.948
AOP52772.1
Thiol:disulfide oxidoreductase related to ResA.
  
  
 0.930
AOP52773.1
Cytochrome c-type biogenesis protein CcdA (DsbD-like protein).
  
  
 0.913
AOP52771.1
Hypothetical protein; Putative, related to broad specificity phosphatases COG0406.
  
    0.906
AOP52774.1
Ccs1/ResB-related putative cytochrome C-type biogenesis protein.
  
  
 0.889
AOP52895.1
Siroheme synthase; Precorrin-2 oxidase; Sirohydrochlorin ferrochelatase; Uroporphyrinogen-III methyltransferase.
 
   
 0.871
AOP52775.1
Cytochrome c-type biogenesis protein CcsA/ResC.
 
  
 0.817
hemE
Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.757
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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