Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (350 aa)    
Predicted Functional Partners:
lipB
Octanoate-[acyl-carrier-protein]-protein-N-octan oyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  
 0.997
AOP54344.1
Lipoate-protein ligase A.
  
 
 0.945
AOP53675.1
Transmembrane protein; Clustered with lipoate gene.
       0.746
AOP53679.1
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 
 
 0.735
gcvH-2
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.735
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.733
AOP53680.1
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.
  
 0.703
AOP53428.1
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase E1 component.
 
 
 0.701
AOP51824.1
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 
 
 0.675
AOP55380.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 
 0.582
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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