Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pepACytosol aminopeptidase PepA; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (496 aa)    
Predicted Functional Partners:
AOP53680.1
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.
  
  
 0.701
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
       0.690
AOP53679.1
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
  
  
 0.688
AOP54647.1
Beta-hexosaminidase.
    
 0.586
AOP52149.1
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); Belongs to the GcvP family.
  
  
 0.558
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
  0.529
AOP53428.1
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase E1 component.
  
  
 0.523
AOP53852.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 
 0.522
AOP53685.1
Putative iron binding protein from the HesB_IscA_SufA family; Belongs to the HesB/IscA family.
 
  
 0.505
ychF
GTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
    0.504
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
Server load: low (28%) [HD]