Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOP53895.116S rRNA (cytosine(967)-C(5))-methyltransferase. (492 aa)    
Predicted Functional Partners:
AOP53894.1
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
    0.950
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
  
 0.950
AOP53897.1
Helicase PriA essential for oriC/DnaA-independent DNA replication.
 
    0.880
rpoZ
DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 0.879
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.873
AOP53893.1
Riboflavin transporter PnuX.
  
  
 0.867
AOP53899.1
Phosphopantothenoylcysteine synthetase.
  
    0.798
whiA
Cytoplasmic hypothetical protein; Involved in cell division and chromosome segregation.
 
   
 0.797
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.797
AOP54245.1
tRNA pseudouridine synthase B.
 
 
 0.774
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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