STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuKu domain protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (295 aa)    
Predicted Functional Partners:
AOP54805.1
ATP-dependent DNA ligase clustered with Ku protein, LigD.
 
  
 0.963
AOP53080.1
ATP-dependent DNA ligase LigC.
 
  
 0.900
AOP53079.1
ATP-dependent DNA ligase.
 
  
 0.891
AOP53081.1
ATP-dependent DNA ligase clustered with Ku protein, LigD.
 
  
 0.889
AOP54804.1
Putative short chain dehydrogenase/oxidoreductase.
 
     0.501
AOP55137.1
Hypothetical protein; FIG00449467.
  
    0.447
AOP55217.1
Conserved hypothetical protein-putative membrane protein.
 
     0.445
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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