AOP54846.1 protein (Brevibacterium linens) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

AOP54846.1

Phenylacetic acid degradation-related protein. (169 aa)

Predicted Functional Partners:

AOP54845.1

0.803

AOP54844.1

0.713

AOP52682.1

0.560

AOP51974.1

0.470

AOP51953.1

0.448

AOP52133.1

0.448

AOP54847.1

0.433

AOP51872.1

0.408

AOP51910.1

0.408

AOP55396.1

0.408

Your Current Organism:

Brevibacterium linens

NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOP51872.1	AOP51910.1	BLSMQ_0150	BLSMQ_0188	Phenylacetate-CoA oxygenase/reductase, PaaK subunit.	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	0.416
AOP51872.1	AOP52682.1	BLSMQ_0150	BLSMQ_0970	Phenylacetate-CoA oxygenase/reductase, PaaK subunit.	Enoyl-CoA hydratase [isoleucine degradation]; 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase.	0.543
AOP51872.1	AOP54845.1	BLSMQ_0150	BLSMQ_3143	Phenylacetate-CoA oxygenase/reductase, PaaK subunit.	Uncharacterized protein; COG2050; possibly involved in aromatic compounds catabolism.	0.408
AOP51872.1	AOP54846.1	BLSMQ_0150	BLSMQ_3144	Phenylacetate-CoA oxygenase/reductase, PaaK subunit.	Phenylacetic acid degradation-related protein.	0.408
AOP51872.1	AOP55396.1	BLSMQ_0150	BLSMQ_3698	Phenylacetate-CoA oxygenase/reductase, PaaK subunit.	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	0.542
AOP51910.1	AOP51872.1	BLSMQ_0188	BLSMQ_0150	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	Phenylacetate-CoA oxygenase/reductase, PaaK subunit.	0.416
AOP51910.1	AOP52682.1	BLSMQ_0188	BLSMQ_0970	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	Enoyl-CoA hydratase [isoleucine degradation]; 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase.	0.543
AOP51910.1	AOP54845.1	BLSMQ_0188	BLSMQ_3143	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	Uncharacterized protein; COG2050; possibly involved in aromatic compounds catabolism.	0.408
AOP51910.1	AOP54846.1	BLSMQ_0188	BLSMQ_3144	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	Phenylacetic acid degradation-related protein.	0.408
AOP51910.1	AOP55396.1	BLSMQ_0188	BLSMQ_3698	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	0.464
AOP51953.1	AOP52133.1	BLSMQ_0233	BLSMQ_0415	Putative D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing.	Glycolate dehydrogenase, subunit GlcD.	0.657
AOP51953.1	AOP52682.1	BLSMQ_0233	BLSMQ_0970	Putative D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing.	Enoyl-CoA hydratase [isoleucine degradation]; 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase.	0.556
AOP51953.1	AOP54845.1	BLSMQ_0233	BLSMQ_3143	Putative D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing.	Uncharacterized protein; COG2050; possibly involved in aromatic compounds catabolism.	0.448
AOP51953.1	AOP54846.1	BLSMQ_0233	BLSMQ_3144	Putative D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing.	Phenylacetic acid degradation-related protein.	0.448
AOP51953.1	AOP55396.1	BLSMQ_0233	BLSMQ_3698	Putative D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing.	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.	0.526
AOP51974.1	AOP54846.1	BLSMQ_0254	BLSMQ_3144	Hypothetical protein.	Phenylacetic acid degradation-related protein.	0.470
AOP52133.1	AOP51953.1	BLSMQ_0415	BLSMQ_0233	Glycolate dehydrogenase, subunit GlcD.	Putative D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing.	0.657
AOP52133.1	AOP52682.1	BLSMQ_0415	BLSMQ_0970	Glycolate dehydrogenase, subunit GlcD.	Enoyl-CoA hydratase [isoleucine degradation]; 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase.	0.556
AOP52133.1	AOP54845.1	BLSMQ_0415	BLSMQ_3143	Glycolate dehydrogenase, subunit GlcD.	Uncharacterized protein; COG2050; possibly involved in aromatic compounds catabolism.	0.448
AOP52133.1	AOP54846.1	BLSMQ_0415	BLSMQ_3144	Glycolate dehydrogenase, subunit GlcD.	Phenylacetic acid degradation-related protein.	0.448

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Network Stats

number of nodes:

11

number of edges:

38

average node degree:

6.91

avg. local clustering coefficient:

0.966

expected number of edges:

33

PPI enrichment p-value:

0.24

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

8 of 104

1.18

1.4

2.81e-06

GO:0019538

Protein metabolic process

10 of 228

0.93

1.0

2.09e-06

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 254

0.84

0.81

2.41e-05

GO:1901566

Organonitrogen compound biosynthetic process

9 of 276

0.8

0.75

4.42e-05

GO:1901564

Organonitrogen compound metabolic process

11 of 473

0.66

0.61

8.82e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 53

1.41

1.88

1.33e-06

GO:0019843

rRNA binding

4 of 41

1.28

0.86

0.0080

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

7 of 55

1.4

1.96

3.12e-07

GO:0044391

Ribosomal subunit

2 of 15

1.42

0.64

0.0470

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:106

Structural constituent of ribosome

7 of 54

1.4

2.01

1.74e-07

CL:103

Structural constituent of ribosome, and Elongation factor

8 of 68

1.36

1.99

5.59e-08

CL:85

Mixed, incl. Translation, and Oxidative phosphorylation

10 of 168

1.07

1.33

5.27e-08

CL:146

Ribosomal protein

3 of 17

1.54

1.13

0.0031

CL:108

Structural constituent of ribosome

4 of 42

1.27

1.05

0.0016

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 54

1.4

1.97

3.20e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 42

1.51

2.28

1.22e-07

GOCC:0044391

Ribosomal subunit

5 of 22

1.65

2.05

9.09e-06

GOCC:0022626

Cytosolic ribosome

4 of 16

1.69

1.85

5.67e-05

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 10

1.77

1.5

0.00070

GOCC:0015934

Large ribosomal subunit

2 of 10

1.59

0.77

0.0277

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 53

1.41

1.96

4.58e-07

KW-0699

rRNA-binding

4 of 39

1.3

1.03

0.0023

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