STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP54905.15-formyltetrahydrofolate cyclo-ligase. (224 aa)    
Predicted Functional Partners:
AOP54904.1
UTP--glucose-1-phosphate uridylyltransferase.
     
 0.717
AOP54903.1
Ribosomal-protein-S5p-alanine acetyltransferase.
  
    0.693
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.614
fhs
Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
   
 
 0.590
pheT
Phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.569
AOP53263.1
Fructose-1,6-bisphosphatase, GlpX type.
 
   
 0.559
AOP54044.1
Hypothetical protein; COG1496; Belongs to the multicopper oxidase YfiH/RL5 family.
 
   
 0.531
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
   0.523
ybeY
Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.523
AOP54663.1
TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA.
 
  
 0.496
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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