STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP55202.1Pyruvate oxidase [ubiquinone, cytochrome]; Belongs to the TPP enzyme family. (571 aa)    
Predicted Functional Partners:
AOP54356.1
Acetolactate synthase small subunit.
 
 0.650
AOP53878.1
Glutamate synthase [NADPH] large chain.
  
  
 0.541
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.505
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.497
AOP54841.1
Benzoylformate decarboxylase; Belongs to the TPP enzyme family.
 
   
 0.464
AOP55203.1
DNA or RNA helicases of superfamily II.
       0.458
AOP52420.1
Catalase; Belongs to the catalase family.
  
  0.456
AOP53613.1
Transcriptional regulator, MerR family.
  
    0.454
AOP55320.1
Putative transcriptional regulator.
  
    0.454
AOP54349.1
Branched-chain amino acid aminotransferase.
  
   0.450
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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