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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOP55450.1Hypothetical protein. (624 aa)    
Predicted Functional Partners:
AOP53426.1
Hypothetical protein; FIG00447877.
  
 
 0.528
AOP54232.1
Hypothetical protein; FIG00820747.
 
     0.500
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.498
AOP52419.1
Hypothetical protein; Similarities with tr|Q08294 Saccharomyces cerevisiae YOL155c.
 
   0.468
AOP55103.1
GrpB domain protein.
 
     0.464
AOP53868.1
Dephospho-CoA kinase.
 
     0.458
AOP54954.1
Phenylacetic acid degradation operon negative regulatory protein PaaX.
 
    0.455
AOP55537.1
N-acetylmuramoyl-L-alanine amidase.
  
  
 0.452
AOP55432.1
Hypothetical protein; FIG111991.
   
 
 0.451
AOP53962.1
ComEC/Rec2-related protein.
 
   
 0.436
Your Current Organism:
Brevibacterium linens
NCBI taxonomy Id: 1703
Other names: ATCC 9172, B. linens, Bacterium linens, Brevibacterium sp. RS16(2010), CIP 101125, Corynebacterium sp. AC474, DSM 20425, HAMBI 2038, IFO 12142, NBRC 12142, NRRL B-4210, VKM Ac-2112
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