STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerCHypothetical protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (305 aa)    
Predicted Functional Partners:
topA
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
  
  
 0.856
KPK47639.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
     
 0.818
KPK45683.1
3-dehydroquinate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the type-II 3-dehydroquinase family.
       0.778
KPK45680.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.757
KPK45678.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.544
KPK45679.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.544
KPK47926.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.524
KPK46011.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.512
KPK47626.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.452
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.440
Your Current Organism:
Dehalococcoidia bacterium SM23282
NCBI taxonomy Id: 1703396
Other names: D. bacterium SM23_28_2, Dehalococcoidia bacterium SM23_28_2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.