STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPK64239.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1560 aa)    
Predicted Functional Partners:
nrdR
NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.550
KPK62373.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.546
KPK64491.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.520
KPK64241.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.500
rpsT
Hypothetical protein; Binds directly to 16S ribosomal RNA.
       0.474
KPK64824.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.473
KPK64443.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.472
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
 
     0.463
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.437
rpsF
Hypothetical protein; Binds together with S18 to 16S ribosomal RNA.
       0.400
Your Current Organism:
candidate division WOR3
NCBI taxonomy Id: 1703779
Other names: c. division WOR_3 bacterium SM23_42, candidate division WOR_3 bacterium SM23_42
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