STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPK63242.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)    
Predicted Functional Partners:
KPK63172.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.999
KPK62438.1
Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]
    
 0.999
KPK64142.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
KPK62679.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
KPK62223.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.952
KPK63243.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.791
leuS
leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...]
       0.717
ligA
Aromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
     
 0.668
KPK63245.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.610
KPK62224.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.602
Your Current Organism:
candidate division WOR3
NCBI taxonomy Id: 1703779
Other names: c. division WOR_3 bacterium SM23_42, candidate division WOR_3 bacterium SM23_42
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