| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALJ56638.1 | gmhA | AMD24_00465 | AMD24_00789 | D-beta-D-heptose 1-phosphate adenylyltransferase. | Phosphoheptose isomerase. | 0.909 |
| ALJ56638.1 | gmhB | AMD24_00465 | AMD24_00096 | D-beta-D-heptose 1-phosphate adenylyltransferase. | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | 0.978 |
| ALJ56638.1 | hldE_1 | AMD24_00465 | AMD24_00097 | D-beta-D-heptose 1-phosphate adenylyltransferase. | Bifunctional protein HldE. | 0.973 |
| ALJ56638.1 | rfaF | AMD24_00465 | AMD24_00239 | D-beta-D-heptose 1-phosphate adenylyltransferase. | ADP-heptose--LPS heptosyltransferase 2. | 0.562 |
| gmhA | ALJ56638.1 | AMD24_00789 | AMD24_00465 | Phosphoheptose isomerase. | D-beta-D-heptose 1-phosphate adenylyltransferase. | 0.909 |
| gmhA | gmhB | AMD24_00789 | AMD24_00096 | Phosphoheptose isomerase. | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | 0.983 |
| gmhA | hldE_1 | AMD24_00789 | AMD24_00097 | Phosphoheptose isomerase. | Bifunctional protein HldE. | 0.805 |
| gmhA | rfaF | AMD24_00789 | AMD24_00239 | Phosphoheptose isomerase. | ADP-heptose--LPS heptosyltransferase 2. | 0.516 |
| gmhB | ALJ56638.1 | AMD24_00096 | AMD24_00465 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | D-beta-D-heptose 1-phosphate adenylyltransferase. | 0.978 |
| gmhB | gmhA | AMD24_00096 | AMD24_00789 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | Phosphoheptose isomerase. | 0.983 |
| gmhB | hisA | AMD24_00096 | AMD24_00264 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.634 |
| gmhB | hisD | AMD24_00096 | AMD24_00026 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.697 |
| gmhB | hisF | AMD24_00096 | AMD24_00076 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.631 |
| gmhB | hisH1 | AMD24_00096 | AMD24_00265 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.692 |
| gmhB | hldE_1 | AMD24_00096 | AMD24_00097 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | Bifunctional protein HldE. | 0.823 |
| gmhB | kdsB | AMD24_00096 | AMD24_00095 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.783 |
| gmhB | polX | AMD24_00096 | AMD24_00278 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | DNA polymerase/3'-5' exonuclease PolX. | 0.918 |
| gmhB | rfaF | AMD24_00096 | AMD24_00239 | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | ADP-heptose--LPS heptosyltransferase 2. | 0.946 |
| hisA | gmhB | AMD24_00264 | AMD24_00096 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase. | 0.634 |
| hisA | hisD | AMD24_00264 | AMD24_00026 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.935 |