| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALJ56744.1 | mlaE | AMD24_00575 | AMD24_00576 | Putative ABC transporter ATP-binding protein. | Putative phospholipid ABC transporter permease protein MlaE; Belongs to the MlaE permease family. | 0.999 |
| ALJ56744.1 | msbA | AMD24_00575 | AMD24_00133 | Putative ABC transporter ATP-binding protein. | Lipid A export ATP-binding/permease protein MsbA. | 0.780 |
| acpP | fabG | AMD24_00817 | AMD24_00454 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.529 |
| acpP | glyA | AMD24_00817 | AMD24_00614 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.733 |
| acpP | moeZ | AMD24_00817 | AMD24_00524 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.503 |
| acpP | msbA | AMD24_00817 | AMD24_00133 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Lipid A export ATP-binding/permease protein MsbA. | 0.606 |
| dnaK | glyA | AMD24_00054 | AMD24_00614 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.515 |
| dnaK | moeZ | AMD24_00054 | AMD24_00524 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.525 |
| dnaK | msbA | AMD24_00054 | AMD24_00133 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Lipid A export ATP-binding/permease protein MsbA. | 0.603 |
| dnaK | yajL | AMD24_00054 | AMD24_00533 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein YajL. | 0.421 |
| fabG | acpP | AMD24_00454 | AMD24_00817 | 3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.529 |
| fabG | glyA | AMD24_00454 | AMD24_00614 | 3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.558 |
| fabG | moeZ | AMD24_00454 | AMD24_00524 | 3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.579 |
| fabG | msbA | AMD24_00454 | AMD24_00133 | 3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Lipid A export ATP-binding/permease protein MsbA. | 0.598 |
| glyA | acpP | AMD24_00614 | AMD24_00817 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.733 |
| glyA | dnaK | AMD24_00614 | AMD24_00054 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.515 |
| glyA | fabG | AMD24_00614 | AMD24_00454 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.558 |
| glyA | moeZ | AMD24_00614 | AMD24_00524 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.760 |
| glyA | msbA | AMD24_00614 | AMD24_00133 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Lipid A export ATP-binding/permease protein MsbA. | 0.597 |
| glyA | purH | AMD24_00614 | AMD24_00134 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Bifunctional purine biosynthesis protein PurH. | 0.990 |