| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALJ56848.1 | frdA | AMD24_00683 | AMD24_00682 | Hypothetical protein. | Fumarate reductase flavoprotein subunit. | 0.998 |
| ALJ56848.1 | frdB | AMD24_00683 | AMD24_00681 | Hypothetical protein. | Fumarate reductase iron-sulfur subunit. | 0.998 |
| ALJ56848.1 | sucC | AMD24_00683 | AMD24_00322 | Hypothetical protein. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.909 |
| ALJ56848.1 | sucD | AMD24_00683 | AMD24_00321 | Hypothetical protein. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.909 |
| accC | citZ | AMD24_00337 | AMD24_00320 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Citrate synthase 2; Belongs to the citrate synthase family. | 0.832 |
| accC | pdhC_1 | AMD24_00337 | AMD24_00119 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.912 |
| accC | pdhC_2 | AMD24_00337 | AMD24_00724 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.912 |
| accC | sucC | AMD24_00337 | AMD24_00322 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.833 |
| accC | sucD | AMD24_00337 | AMD24_00321 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.818 |
| citZ | accC | AMD24_00320 | AMD24_00337 | Citrate synthase 2; Belongs to the citrate synthase family. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.832 |
| citZ | frdA | AMD24_00320 | AMD24_00682 | Citrate synthase 2; Belongs to the citrate synthase family. | Fumarate reductase flavoprotein subunit. | 0.839 |
| citZ | frdB | AMD24_00320 | AMD24_00681 | Citrate synthase 2; Belongs to the citrate synthase family. | Fumarate reductase iron-sulfur subunit. | 0.860 |
| citZ | pdhC_1 | AMD24_00320 | AMD24_00119 | Citrate synthase 2; Belongs to the citrate synthase family. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.951 |
| citZ | pdhC_2 | AMD24_00320 | AMD24_00724 | Citrate synthase 2; Belongs to the citrate synthase family. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.951 |
| citZ | sucA | AMD24_00320 | AMD24_00371 | Citrate synthase 2; Belongs to the citrate synthase family. | 2-oxoglutarate dehydrogenase E1 component. | 0.828 |
| citZ | sucB | AMD24_00320 | AMD24_00370 | Citrate synthase 2; Belongs to the citrate synthase family. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex. | 0.538 |
| citZ | sucC | AMD24_00320 | AMD24_00322 | Citrate synthase 2; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.972 |
| citZ | sucD | AMD24_00320 | AMD24_00321 | Citrate synthase 2; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.870 |
| frdA | ALJ56848.1 | AMD24_00682 | AMD24_00683 | Fumarate reductase flavoprotein subunit. | Hypothetical protein. | 0.998 |
| frdA | citZ | AMD24_00682 | AMD24_00320 | Fumarate reductase flavoprotein subunit. | Citrate synthase 2; Belongs to the citrate synthase family. | 0.839 |