| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALJ56604.1 | ALJ56869.1 | AMD24_00429 | AMD24_00705 | Putative metallo-hydrolase. | Putative metallo-hydrolase. | 0.928 |
| ALJ56604.1 | glyA | AMD24_00429 | AMD24_00614 | Putative metallo-hydrolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.452 |
| ALJ56604.1 | guaA | AMD24_00429 | AMD24_00593 | Putative metallo-hydrolase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.488 |
| ALJ56604.1 | moeZ | AMD24_00429 | AMD24_00524 | Putative metallo-hydrolase. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.641 |
| ALJ56869.1 | ALJ56604.1 | AMD24_00705 | AMD24_00429 | Putative metallo-hydrolase. | Putative metallo-hydrolase. | 0.928 |
| ALJ56869.1 | glyA | AMD24_00705 | AMD24_00614 | Putative metallo-hydrolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.452 |
| ALJ56869.1 | guaA | AMD24_00705 | AMD24_00593 | Putative metallo-hydrolase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.488 |
| ALJ56869.1 | moeZ | AMD24_00705 | AMD24_00524 | Putative metallo-hydrolase. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.641 |
| glyA | ALJ56604.1 | AMD24_00614 | AMD24_00429 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Putative metallo-hydrolase. | 0.452 |
| glyA | ALJ56869.1 | AMD24_00614 | AMD24_00705 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Putative metallo-hydrolase. | 0.452 |
| glyA | guaA | AMD24_00614 | AMD24_00593 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.688 |
| glyA | moeZ | AMD24_00614 | AMD24_00524 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.760 |
| guaA | ALJ56604.1 | AMD24_00593 | AMD24_00429 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Putative metallo-hydrolase. | 0.488 |
| guaA | ALJ56869.1 | AMD24_00593 | AMD24_00705 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Putative metallo-hydrolase. | 0.488 |
| guaA | glyA | AMD24_00593 | AMD24_00614 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.688 |
| guaA | moeZ | AMD24_00593 | AMD24_00524 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.665 |
| moeZ | ALJ56604.1 | AMD24_00524 | AMD24_00429 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Putative metallo-hydrolase. | 0.641 |
| moeZ | ALJ56869.1 | AMD24_00524 | AMD24_00705 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Putative metallo-hydrolase. | 0.641 |
| moeZ | glyA | AMD24_00524 | AMD24_00614 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.760 |
| moeZ | guaA | AMD24_00524 | AMD24_00593 | Putative adenylyltransferase/sulfurtransferase MoeZ. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.665 |