| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysO | moeZ | AMD24_00417 | AMD24_00524 | Sulfur carrier protein CysO. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.990 |
| cysO | thiG_1 | AMD24_00417 | AMD24_00594 | Sulfur carrier protein CysO. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.627 |
| cysO | thiG_2 | AMD24_00417 | AMD24_00595 | Sulfur carrier protein CysO. | Thiazole synthase. | 0.627 |
| guaA | moeZ | AMD24_00593 | AMD24_00524 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.665 |
| guaA | thiD | AMD24_00593 | AMD24_00285 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.420 |
| guaA | thiG_1 | AMD24_00593 | AMD24_00594 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.419 |
| guaA | thiG_2 | AMD24_00593 | AMD24_00595 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Thiazole synthase. | 0.419 |
| moeZ | cysO | AMD24_00524 | AMD24_00417 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Sulfur carrier protein CysO. | 0.990 |
| moeZ | guaA | AMD24_00524 | AMD24_00593 | Putative adenylyltransferase/sulfurtransferase MoeZ. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.665 |
| moeZ | mqnE_1 | AMD24_00524 | AMD24_00288 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.618 |
| moeZ | mqnE_2 | AMD24_00524 | AMD24_00441 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.618 |
| moeZ | thiD | AMD24_00524 | AMD24_00285 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.814 |
| moeZ | thiG_1 | AMD24_00524 | AMD24_00594 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.921 |
| moeZ | thiG_2 | AMD24_00524 | AMD24_00595 | Putative adenylyltransferase/sulfurtransferase MoeZ. | Thiazole synthase. | 0.921 |
| mqnE_1 | moeZ | AMD24_00288 | AMD24_00524 | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.618 |
| mqnE_1 | thiD | AMD24_00288 | AMD24_00285 | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.611 |
| mqnE_1 | thiG_1 | AMD24_00288 | AMD24_00594 | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.690 |
| mqnE_1 | thiG_2 | AMD24_00288 | AMD24_00595 | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Thiazole synthase. | 0.690 |
| mqnE_2 | moeZ | AMD24_00441 | AMD24_00524 | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | Putative adenylyltransferase/sulfurtransferase MoeZ. | 0.618 |
| mqnE_2 | thiG_1 | AMD24_00441 | AMD24_00594 | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.690 |