node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMQ22_00507 | AMQ22_00510 | APG08_00292 | APG08_00289 | HTH asnC-type domain-containing protein. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | 0.511 |
AMQ22_00507 | AMQ22_00511 | APG08_00292 | APG08_00288 | HTH asnC-type domain-containing protein. | Major Facilitator Superfamily protein. | 0.481 |
AMQ22_00507 | folD | APG08_00292 | APG08_00290 | HTH asnC-type domain-containing protein. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.511 |
AMQ22_00507 | glyA | APG08_00292 | APG08_00291 | HTH asnC-type domain-containing protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.511 |
AMQ22_00510 | AMQ22_00507 | APG08_00289 | APG08_00292 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | HTH asnC-type domain-containing protein. | 0.511 |
AMQ22_00510 | AMQ22_00511 | APG08_00289 | APG08_00288 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | Major Facilitator Superfamily protein. | 0.723 |
AMQ22_00510 | folD | APG08_00289 | APG08_00290 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.952 |
AMQ22_00510 | glyA | APG08_00289 | APG08_00291 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.962 |
AMQ22_00511 | AMQ22_00507 | APG08_00288 | APG08_00292 | Major Facilitator Superfamily protein. | HTH asnC-type domain-containing protein. | 0.481 |
AMQ22_00511 | AMQ22_00510 | APG08_00288 | APG08_00289 | Major Facilitator Superfamily protein. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | 0.723 |
AMQ22_00511 | folD | APG08_00288 | APG08_00290 | Major Facilitator Superfamily protein. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.723 |
AMQ22_00511 | glyA | APG08_00288 | APG08_00291 | Major Facilitator Superfamily protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.723 |
folD | AMQ22_00507 | APG08_00290 | APG08_00292 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | HTH asnC-type domain-containing protein. | 0.511 |
folD | AMQ22_00510 | APG08_00290 | APG08_00289 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | 0.952 |
folD | AMQ22_00511 | APG08_00290 | APG08_00288 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Major Facilitator Superfamily protein. | 0.723 |
folD | glyA | APG08_00290 | APG08_00291 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.973 |
glyA | AMQ22_00507 | APG08_00291 | APG08_00292 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | HTH asnC-type domain-containing protein. | 0.511 |
glyA | AMQ22_00510 | APG08_00291 | APG08_00289 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase. | 0.962 |
glyA | AMQ22_00511 | APG08_00291 | APG08_00288 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Major Facilitator Superfamily protein. | 0.723 |
glyA | folD | APG08_00291 | APG08_00290 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.973 |