STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMQ22_00302Methyl-coenzyme M reductase subunit alpha; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (553 aa)    
Predicted Functional Partners:
AMQ22_00303
Methyl-coenzyme M reductase subunit gamma.
  
 0.999
AMQ22_00305
Methyl-coenzyme M reductase subunit beta.
  
 0.999
AMQ22_00304
Methyl-coenzyme M reductase operon protein.
  
 
 0.992
mcrC
Methyl-coenzyme M reductase operon protein C.
  
 
 0.974
AMQ22_00755
CoB--CoM heterodisulfide reductase iron-sulfur subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.808
AMQ22_00753
Hydrogenase MvhADGHdrABC CoB-CoM heterodisulfide reductase subunit B.
    
 0.793
AMQ22_01243
F420-reducing hydrogenase, subunit beta.
     
 0.772
mtaC
Methanol--corrinoid protein.
     
 0.772
AMQ22_00754
Hydrogenase MvhADGHdrABC CoB-CoM heterodisulfide reductase subunit C.
    
 0.771
AMQ22_00322
Hydrogenase MvhADGHdrABC F420-non-reducing hydrogenase subunit G.
   
 
 0.765
Your Current Organism:
Methanofastidiosum methylthiophilus
NCBI taxonomy Id: 1705564
Other names: Arc I group archaeon ADurb1013_Bin02101, Arc I group archaeon ADurb1113_Bin01801, Arc I group archaeon ADurb1213_Bin02801, Arc I group archaeon B03fssc0709_Meth_Bin005, Arc I group archaeon B15fssc0709_Meth_Bin003, Arc I group archaeon BMIXfssc0709_Meth_Bin006, Arc I group archaeon U1lsi0528_Bin055, Arc I group archaeon U1lsi0528_Bin089, C. Methanofastidiosum methylthiophilus, Ca. Methanofastidiosum methylthiophilus, Candidatus Methanofastidiosum methylthiophilus, WSA2 group archaeon U1lsi0528_Bin055, WSA2 group archaeon U1lsi0528_Bin089
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