STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtaAMethylcobamide:CoM methyltransferase MtaA. (341 aa)    
Predicted Functional Partners:
mttC
Trimethylamine corrinoid protein.
 
 0.961
mtsA
Methylated-thiol--coenzyme M methyltransferase.
 
  
0.932
cobA
Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.922
hemC
Probable porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.827
APG08_00517
annotation not available
 
  
 0.767
mtaC
Methanol--corrinoid protein.
 
  
 
0.762
AMQ22_00302
Methyl-coenzyme M reductase subunit alpha; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
     
 0.757
AMQ22_00305
Methyl-coenzyme M reductase subunit beta.
     
 0.753
AMQ22_00303
Methyl-coenzyme M reductase subunit gamma.
     
 0.750
AMQ22_00495
4Fe-4S dicluster domain protein.
 
   
 0.727
Your Current Organism:
Methanofastidiosum methylthiophilus
NCBI taxonomy Id: 1705564
Other names: Arc I group archaeon ADurb1013_Bin02101, Arc I group archaeon ADurb1113_Bin01801, Arc I group archaeon ADurb1213_Bin02801, Arc I group archaeon B03fssc0709_Meth_Bin005, Arc I group archaeon B15fssc0709_Meth_Bin003, Arc I group archaeon BMIXfssc0709_Meth_Bin006, Arc I group archaeon U1lsi0528_Bin055, Arc I group archaeon U1lsi0528_Bin089, C. Methanofastidiosum methylthiophilus, Ca. Methanofastidiosum methylthiophilus, Candidatus Methanofastidiosum methylthiophilus, WSA2 group archaeon U1lsi0528_Bin055, WSA2 group archaeon U1lsi0528_Bin089
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.