STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (172 aa)    
Predicted Functional Partners:
argB_2
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
 0.982
APG08_00760
annotation not available
 
 
 0.971
argB_1
Putative [LysW]-aminoadipate/[LysW]-glutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.
 
 0.929
fumC_2
Argininosuccinate lyase.
  
 
 0.912
hemL_1
Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
  
 
 0.868
hemL_3
Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.868
argF_2
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.767
lysK
Putative [LysW]-lysine/[LysW]-ornithine hydrolase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
  
 0.755
AMQ22_01255
Putative metallohydrolase.
  
 0.737
AMQ22_01216
Argininosuccinate synthase.
  
  
 0.714
Your Current Organism:
Methanofastidiosum methylthiophilus
NCBI taxonomy Id: 1705564
Other names: Arc I group archaeon ADurb1013_Bin02101, Arc I group archaeon ADurb1113_Bin01801, Arc I group archaeon ADurb1213_Bin02801, Arc I group archaeon B03fssc0709_Meth_Bin005, Arc I group archaeon B15fssc0709_Meth_Bin003, Arc I group archaeon BMIXfssc0709_Meth_Bin006, Arc I group archaeon U1lsi0528_Bin055, Arc I group archaeon U1lsi0528_Bin089, C. Methanofastidiosum methylthiophilus, Ca. Methanofastidiosum methylthiophilus, Candidatus Methanofastidiosum methylthiophilus, WSA2 group archaeon U1lsi0528_Bin055, WSA2 group archaeon U1lsi0528_Bin089
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