STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIProbable tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (367 aa)    
Predicted Functional Partners:
trm4
tRNA (Cytosine(48)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
    0.875
AMQ22_00336
O-phospho-L-seryl-tRNA:Cys-tRNA synthase.
 
   
 0.832
moeB
Putative adenylyltransferase.
    
 0.820
AMQ22_00334
Digeranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
  
    0.782
AMQ22_00337
Uncharacterized protein.
       0.773
AMQ22_00333
CRISPR-associated exonuclease Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
       0.718
AMQ22_01615
Molybdopterin biosynthesis-like protein MoeZ.
 
  
 0.693
APG08_01361
annotation not available
 
  
 0.692
APG08_01216
annotation not available
 
  
 0.687
AMQ22_01943
Uncharacterized protein.
 
  
  0.643
Your Current Organism:
Methanofastidiosum methylthiophilus
NCBI taxonomy Id: 1705564
Other names: Arc I group archaeon ADurb1013_Bin02101, Arc I group archaeon ADurb1113_Bin01801, Arc I group archaeon ADurb1213_Bin02801, Arc I group archaeon B03fssc0709_Meth_Bin005, Arc I group archaeon B15fssc0709_Meth_Bin003, Arc I group archaeon BMIXfssc0709_Meth_Bin006, Arc I group archaeon U1lsi0528_Bin055, Arc I group archaeon U1lsi0528_Bin089, C. Methanofastidiosum methylthiophilus, Ca. Methanofastidiosum methylthiophilus, Candidatus Methanofastidiosum methylthiophilus, WSA2 group archaeon U1lsi0528_Bin055, WSA2 group archaeon U1lsi0528_Bin089
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