STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase-3 nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
SEI44501.1
Hydrogenase nickel incorporation protein HypB.
 
 0.994
SEI44627.1
Hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.985
SEI44527.1
Nickel-dependent hydrogenase.
 
 
 0.984
SEI44461.1
Hydrogenase maturation protein HypD; Belongs to the HypD family.
 
  
 0.962
SEI44474.1
Hydrogenase maturation protein HypC.
 
  
 0.962
SEI44452.1
Hydrogenase maturation protein, carbamoyl dehydratase HypE.
 
  
 0.960
SEI44491.1
Hydrogenase maturation protein, carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.959
SEI44600.1
Hydrogenase maturation protease.
 
 
 0.955
SEI44586.1
Hydrogenase expression/formation protein HypC.
 
  
 0.926
SEI44537.1
[NiFe] hydrogenase assembly chaperone, HybE family.
 
  
 0.925
Your Current Organism:
Azotobacter beijerinckii
NCBI taxonomy Id: 170623
Other names: A. beijerinckii, ATCC 19360, CIP 106282, DSM 378, JCM 20742, NCAIM B.01800, NRRL B-14367, NRRL B-14640
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.