node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEI46161.1 | SEI66264.1 | SAMN04244579_00594 | SAMN04244579_01563 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.680 |
SEI46161.1 | SEI74896.1 | SAMN04244579_00594 | SAMN04244579_01873 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Uncharacterized conserved protein YbbK, DUF523 family. | 0.695 |
SEI46161.1 | xpt | SAMN04244579_00594 | SAMN04244579_03530 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.932 |
SEI58278.1 | SEI66264.1 | SAMN04244579_01241 | SAMN04244579_01563 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.746 |
SEI58278.1 | SEI74896.1 | SAMN04244579_01241 | SAMN04244579_01873 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Uncharacterized conserved protein YbbK, DUF523 family. | 0.692 |
SEI58278.1 | SEI87476.1 | SAMN04244579_01241 | SAMN04244579_02307 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Phosphoribosyl transferase domain-containing protein. | 0.512 |
SEI58278.1 | SEI88751.1 | SAMN04244579_01241 | SAMN04244579_02343 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 40-residue YVTN family beta-propeller repeat-containing protein. | 0.915 |
SEI58278.1 | SEJ36793.1 | SAMN04244579_01241 | SAMN04244579_04098 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | DNA-O6-methylguanine--protein-cysteine S-methyltransferase /Transcriptional regulator Ada. | 0.633 |
SEI58278.1 | xpt | SAMN04244579_01241 | SAMN04244579_03530 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.936 |
SEI66264.1 | SEI46161.1 | SAMN04244579_01563 | SAMN04244579_00594 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.680 |
SEI66264.1 | SEI58278.1 | SAMN04244579_01563 | SAMN04244579_01241 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.746 |
SEI66264.1 | SEI74896.1 | SAMN04244579_01563 | SAMN04244579_01873 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Uncharacterized conserved protein YbbK, DUF523 family. | 0.694 |
SEI66264.1 | SEI87476.1 | SAMN04244579_01563 | SAMN04244579_02307 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Phosphoribosyl transferase domain-containing protein. | 0.810 |
SEI66264.1 | SEI88751.1 | SAMN04244579_01563 | SAMN04244579_02343 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 40-residue YVTN family beta-propeller repeat-containing protein. | 0.680 |
SEI66264.1 | SEJ36793.1 | SAMN04244579_01563 | SAMN04244579_04098 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | DNA-O6-methylguanine--protein-cysteine S-methyltransferase /Transcriptional regulator Ada. | 0.735 |
SEI66264.1 | mtaD | SAMN04244579_01563 | SAMN04244579_01638 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Cytosine/adenosine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.982 |
SEI66264.1 | xpt | SAMN04244579_01563 | SAMN04244579_03530 | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.815 |
SEI74896.1 | SEI46161.1 | SAMN04244579_01873 | SAMN04244579_00594 | Uncharacterized conserved protein YbbK, DUF523 family. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.695 |
SEI74896.1 | SEI58278.1 | SAMN04244579_01873 | SAMN04244579_01241 | Uncharacterized conserved protein YbbK, DUF523 family. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.692 |
SEI74896.1 | SEI66264.1 | SAMN04244579_01873 | SAMN04244579_01563 | Uncharacterized conserved protein YbbK, DUF523 family. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.694 |