STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXH72631.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (447 aa)    
Predicted Functional Partners:
KXH72612.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.940
polB
Hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
  
 
 
 0.921
topA
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
   
 
 0.830
KXH72630.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
rps15
30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.749
KXH72232.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.674
kae1
UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family.
     
 0.642
KXH70804.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.623
KXH72622.1
Hypothetical protein; Involved in regulation of DNA replication.
 
   
 0.611
dnaG
Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
 
  
 0.608
Your Current Organism:
Thorarchaeota archaeon SMTZ145
NCBI taxonomy Id: 1706444
Other names: C. Thorarchaeota archaeon SMTZ1-45, Candidatus Thorarchaeota archaeon SMTZ1-45, Thorarchaeota archaeon SMTZ1-45
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