STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXH72258.1Hypothetical protein; Involved in DNA damage repair. (425 aa)    
Predicted Functional Partners:
KXH75500.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.666
priS
Hypothetical protein; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May a [...]
 
     0.656
KXH72624.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.642
KXH70221.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.642
KXH71098.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.633
KXH72622.1
Hypothetical protein; Involved in regulation of DNA replication.
  
     0.631
KXH72657.1
Hypothetical protein; Involved in regulation of DNA replication.
  
     0.631
KXH75118.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.629
nac
Hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.609
dnaG
Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.608
Your Current Organism:
Thorarchaeota archaeon SMTZ145
NCBI taxonomy Id: 1706444
Other names: C. Thorarchaeota archaeon SMTZ1-45, Candidatus Thorarchaeota archaeon SMTZ1-45, Thorarchaeota archaeon SMTZ1-45
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.