STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comATransport ATP-binding protein ComA; Required for induction of competence. Seems to transport the competence-stimulating peptide (CSP) (By similarity); Belongs to the ABC transporter superfamily. HlyB family. (717 aa)    
Predicted Functional Partners:
comB
Transport protein ComB; Required for induction of competence; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.965
spr0466
Conserved hypothetical protein, truncation; blpB.
 
 
 0.873
spr0105
Transporter, truncation.
  
     0.666
spr0108
Conserved hypothetical protein; Similar to ComB protein.
 
 
 0.626
PTS-EIIA
Phosphotransferase system sugar-specific EIIA component.
      
 0.516
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family.
       0.489
spr0467
Conserved hypothetical protein, truncation; blpB.
  
 
 0.469
ABC-NP-4
ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
 
 
  
0.445
ABC-NP-3
ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
 
 
  
0.441
ABC-N/P-5
ABC transporter ATP-binding/membrane spanning protein - unknown substrate.
 
 
  
0.424
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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