Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0075Conserved hypothetical protein; Similar to cell wall-associated serine proteinase. (1161 aa)    
Predicted Functional Partners:
spr0466
Conserved hypothetical protein, truncation; blpB.
      
 0.777
rr08
Response regulator.
     
 0.663
spr1077
Function unknown, truncation.
   
  
 0.604
spr0510
Hypothetical protein.
      
 0.599
spr1403
Hypothetical protein.
     
 0.599
spr1702
Degenerate transposase (orf2).
      
 0.599
spr1730
Hypothetical protein.
      
 0.599
spr0263
Conserved hypothetical protein.
      
 0.594
spr1701
Degenerate transposase (orf1).
      
 0.593
gsp-781
General stress protein GSP-781.
      
 0.588
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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