Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABC-SBP-2ABC transporter solute-binding protein - amino acid transport. (265 aa)    
Predicted Functional Partners:
glnP-5
ABC transporter membrane-spanning permease - glutamine transport.
 
 0.991
glnP
ABC transporter membrane-spanning permease - glutamine transport.
 
 0.980
glnP-7
ABC transporter membrane-spanning permease - glutamine transport.
 
 0.952
glnH
ABC transporter substrate binding protein - glutamine transport.
 
 0.947
ABC-NBD
ABC transporter ATP-binding protein - amino acid transport.
   
  0.943
ABC-MSP-3
ABC transporter membrane-spanning permease - amino acid transport.
    
  0.941
ABC-MSP-13
ABC transporter membrane-spanning permease - aspartate/glutamate transport.
 
 0.933
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.921
glnP-2
ABC transporter membrane-spanning permease - glutamine transport.
 
 0.918
argH
Arginine succinate lyase.
  
  
 0.868
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
Server load: low (14%) [HD]