Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0106Transporter, truncation; Similar to competence factor transporting ATP-binding/permease protein ComA. (644 aa)    
Predicted Functional Partners:
spr0108
Conserved hypothetical protein; Similar to ComB protein.
 
 
 0.963
spr0105
Transporter, truncation.
    0.939
spr0107
Hypothetical protein.
  
    0.815
spr0466
Conserved hypothetical protein, truncation; blpB.
 
 
 0.770
comB
Transport protein ComB; Required for induction of competence; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.764
spr0469
Conserved hypothetical protein, truncation; blpA.
  
    0.764
spr0109
Hypothetical protein.
  
  
 0.675
pstB
ABC transporter ATP-binding protein - phosphate transport; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
     
0.415
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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