Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mutRPositive transcriptional regulator of mutA. (287 aa)    
Predicted Functional Partners:
thiJ
4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein.
      
 0.887
mtlF
Mannitol-specific enzyme IIA component.
      
 0.598
spr0144
Conserved hypothetical protein.
 
   
 0.596
dagA
D-alanine glycine permease.
      
 0.591
rgg
Positive transcriptional regulator of glucosyltransferase and Spp phenotype.
  
   
0.542
rggD
Transcriptional regulator.
  
   
0.507
spr1550
Conserved hypothetical protein; Similar to MutR protein.
  
     0.497
spr1932
Conserved hypothetical protein; Putative permease.
 
   
 0.464
spr0721
Conserved hypothetical protein; Belongs to the Nudix hydrolase family.
  
    0.462
mtlD
Mannitol-1-phosphate 5-dehydrogenase.
      
 0.450
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.