| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdsA | cls | spr0241 | spr0180 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.911 |
| cdsA | pgsA | spr0241 | spr2027 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Phosphotidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.976 |
| cdsA | plsC | spr0241 | spr1465 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Conserved hypothetical protein; Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.942 |
| cdsA | spr1260 | spr0241 | spr1260 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Conserved hypothetical protein; Similar to E. coli extragenic suppressor protein SuhB. | 0.571 |
| cls | cdsA | spr0180 | spr0241 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.911 |
| cls | folC | spr0180 | spr0178 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Dihydrofolate:folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.504 |
| cls | orf47 | spr0180 | spr0181 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Orf47; Induced during competence. | 0.690 |
| cls | pgsA | spr0180 | spr2027 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Phosphotidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.788 |
| cls | plsC | spr0180 | spr1465 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Conserved hypothetical protein; Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.570 |
| cls | spr0179 | spr0180 | spr0179 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Hypothetical protein. | 0.646 |
| cls | spr0182 | spr0180 | spr0182 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Competence-induced protein Ccs4. | 0.544 |
| cls | spr0897 | spr0180 | spr0897 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Hypothetical protein. | 0.740 |
| cls | spr1260 | spr0180 | spr1260 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Conserved hypothetical protein; Similar to E. coli extragenic suppressor protein SuhB. | 0.528 |
| cls | srtA | spr0180 | spr1098 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Sortase; Putative, proposed to perform the peptide cleavage and the transpeptidation during the process of anchoring proteins to Gram-positive bacterial cell walls. | 0.434 |
| folC | cls | spr0178 | spr0180 | Dihydrofolate:folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.504 |
| folC | spr0179 | spr0178 | spr0179 | Dihydrofolate:folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | Hypothetical protein. | 0.793 |
| orf47 | cls | spr0181 | spr0180 | Orf47; Induced during competence. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.690 |
| orf47 | spr0182 | spr0181 | spr0182 | Orf47; Induced during competence. | Competence-induced protein Ccs4. | 0.722 |
| pgsA | cdsA | spr2027 | spr0241 | Phosphotidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.976 |
| pgsA | cls | spr2027 | spr0180 | Phosphotidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.788 |