Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pflFFormate acetyltransferase 3. (815 aa)    
Predicted Functional Partners:
talC
Transaldolase C.
 
  
 0.949
pflE
Pyruvate formate-lyase 3.
 
  
 0.925
gldA
Glycerol dehydrogenase, NAD+ dependent.
  
  
 0.854
pta
Phosphate acetyltransferase.
   
 
 0.849
pflC
Pyruvate-formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.829
aldB
Alpha-acetolactate decarboxylase.
      
 0.792
deoR
DEOR-type transcriptional regulator.
 
 
 
 0.768
adhE
Alcohol-acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.762
PTS-EIIB-2
Phosphotransferase system sugar-specific EIIB component.
 
    0.709
aspC-2
Potential aminotransferase; See also SPR0035.
      
 0.693
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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