Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
asp23Alkaline shock protein. (121 aa)    
Predicted Functional Partners:
spr0400
Conserved hypothetical protein.
 
  
 0.995
rpmB
50S Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
       0.651
spr0391
Conserved hypothetical protein.
 
     0.644
ilvN
Acetolactate synthase small subunit.
       0.634
spr0175
Hypothetical protein; Belongs to the UPF0297 family.
  
  
 0.629
spr1415
Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
 
    0.623
spr1625
Conserved hypothetical protein.
      
 0.610
hk01
Histidine kinase.
   
  
 0.609
frp
Homologue of NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family.
   
  
 0.600
spr1019
Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
 
    0.598
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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