Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTS-EII-10Phosphotransferase system sugar-specific EII component. (114 aa)    
Predicted Functional Partners:
PTS-EII-11
Phosphotransferase system sugar-specific EII component.
 
 0.996
lacE
PTS system, lactose-specific IIBC component.
 
 0.993
lacG
Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.977
ptsH
Histidine-containing phosphocarrier protein of the PTS.
   
 0.926
PTS-EII-9
Phosphotransferase system sugar-specific EII component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
  
 0.922
lacG-2
Phospho-beta-D-galactosidase; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.908
lacF
PTS system, lactose-specific IIA component.
  
  
 
0.905
PTS-EIIB-2
Phosphotransferase system sugar-specific EIIB component.
 
 
 0.900
bgaA
Beta-galactosidase precursor.
     
  0.900
ptcB
Phosphotransferase system system, cellobiose-specific IIB component.
 
 
 0.900
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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