Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
xerDIntegrase/recombinase; Belongs to the 'phage' integrase family. (265 aa)    
Predicted Functional Partners:
xerC
Integrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. Required for resolution of chromosome dimers frequently formed by transformation ; Belongs to the 'phage' integrase family. XerS subfamily.
  
   
 0.900
bltD
Spermine/spermidine acetyltransferase.
      
 0.880
hsdS-2
Type I restriction enzyme EcoKI specificity protein (S protein).
 
  
 0.869
hsdS-3
Type I site-specific deoxyribonuclease chain S.
 
  
 0.832
hsdM
EcoE type I restriction modification enzyme M subunit.
 
   
 0.769
hsdR
EcoA type I restriction-modification enzyme R subunit.
 
   
 0.741
ftsK
Cell division protein; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the difSL recombination site, which is located within the replication terminus region (By similarity). Required for activation of the XerS recombinase, allowing activation of chromosome unlinking by recombination; Belongs to the FtsK/SpoIIIE/SftA family.
 
  
 0.712
hsdS
Type I restriction enzyme.
 
   
 0.496
comFC
Involved in transformation (competence for DNA uptake).
   
    0.495
recJ
Single-stranded DNA-specific exonuclease, 5'-3'.
  
  
 0.480
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.