Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdS-3Type I site-specific deoxyribonuclease chain S. (522 aa)    
Predicted Functional Partners:
hsdM
EcoE type I restriction modification enzyme M subunit.
 
 
 0.998
hsdR
EcoA type I restriction-modification enzyme R subunit.
 
 
 0.997
hsdM-2
Type I restriction modification enzyme methylase subunit.
 
 
 0.986
hsdR-2
Type 1 restriction modification system endonuclease R.
 
 
 0.958
hsdS
Type I restriction enzyme.
  
  
 
0.916
spr1130
Hypothetical protein; Probable endonuclease.
  
  
 0.915
recD
Exonuclease V; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
     
 0.887
xerD
Integrase/recombinase; Belongs to the 'phage' integrase family.
 
  
 0.832
hsdS-2
Type I restriction enzyme EcoKI specificity protein (S protein).
 
    0.683
xerD-2
Recombinase, site specific; Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
    
 0.665
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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