Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ipBacteriocin-like peptide, double glycine cleavage type. (51 aa)    
Predicted Functional Partners:
hk13
Histidine kinase.
   
 
  0.902
pncP
ABC transporter ATP binding protein - unknown substrate.
     
 0.736
spr1737
Conserved hypothetical protein; Putative transcriptional regulator.
   
    0.651
rr13
Response regulator.
   
  
 0.603
spr0466
Conserved hypothetical protein, truncation; blpB.
  
    0.603
blpS
Regulatory protein.
      
 0.598
spr0467
Conserved hypothetical protein, truncation; blpB.
       0.569
spr0468
Conserved hypothetical protein, truncation; blpA.
       0.565
spr0469
Conserved hypothetical protein, truncation; blpA.
       0.565
spr1326
Hypothetical protein.
   
    0.501
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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