Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
brnQBranched-chain amino acid transport system carrier protein; Component of the transport system for branched-chain amino acids. (446 aa)    
Predicted Functional Partners:
spr0159
Conserved hypothetical protein; Similar to autolysin response regulator in Bacillus subtilis.
  
   
 0.938
ABC-MSP
ABC transporter membrane-spanning permease - sugar transport.
      
 0.899
nirC
Formate-nitrate transporter.
      
 0.897
shetA
Exfoliative toxin A.
      
 0.890
codY
Transcriptional pleiotropic repressor; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
      
 0.577
gatA
Glu-tRNAGln amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
      
 0.539
livG
ABC transporter ATP-binding protein - branched chain amino acid transport.
      
 0.523
spr0549
Hypothetical protein.
  
    0.486
spr0550
Conserved hypothetical protein.
       0.485
spr0554
Conserved hypothetical protein; Putative carboxypeptidase.
       0.449
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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