Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0571Conserved hypothetical protein. (187 aa)    
Predicted Functional Partners:
spr0572
Hypothetical protein.
       0.847
nha2
Na+/H+ antiporter.
       0.833
spr0570
Hypothetical protein.
 
     0.819
spr0569
Hypothetical protein.
 
     0.681
spr0574
Conserved hypothetical protein.
     
 0.623
spr1461
Conserved hypothetical protein; Probable oxidase.
  
  
 0.588
ispA
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.578
spr0568
Hypothetical protein.
       0.464
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.