node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adk | tenA | spr0210 | spr0634 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Transcriptional regulator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.429 |
adk | thiM | spr0210 | spr0629 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.425 |
adk | thiM-2 | spr0210 | spr0636 | Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.420 |
pdxK | spr0628 | spr1450 | spr0628 | Pyridoxine kinase. | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | 0.622 |
pdxK | tenA | spr1450 | spr0634 | Pyridoxine kinase. | Transcriptional regulator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.735 |
pdxK | thiE | spr1450 | spr0630 | Pyridoxine kinase. | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.977 |
pdxK | thiE-2 | spr1450 | spr0637 | Pyridoxine kinase. | Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.974 |
pdxK | thiM | spr1450 | spr0629 | Pyridoxine kinase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.660 |
pdxK | thiM-2 | spr1450 | spr0636 | Pyridoxine kinase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.660 |
rpmG | rpmG-2 | spr0876 | spr1822 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.919 |
rpmG | thiE-2 | spr0876 | spr0637 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.413 |
rpmG | thiM | spr0876 | spr0629 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.405 |
rpmG | thiM-2 | spr0876 | spr0636 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.405 |
rpmG-2 | rpmG | spr1822 | spr0876 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.919 |
rpmG-2 | thiE-2 | spr1822 | spr0637 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.413 |
rpmG-2 | thiM | spr1822 | spr0629 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.405 |
rpmG-2 | thiM-2 | spr1822 | spr0636 | 50S Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.411 |
spr0628 | pdxK | spr0628 | spr1450 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Pyridoxine kinase. | 0.622 |
spr0628 | tenA | spr0628 | spr0634 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Transcriptional regulator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.926 |
spr0628 | thiD | spr0628 | spr0638 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Phosphomethylpyrimidine kinase. | 0.962 |