Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABC-NBD-9ABC transporter ATP-binding protein - cobalt or other cation transport. (461 aa)    
Predicted Functional Partners:
spr0633
Conserved hypothetical protein.
 
 
 0.985
spr0631
Conserved hypothetical protein.
 
    0.974
ABC-NBD-4
ABC transporter ATP-binding protein - cobalt transport; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
0.937
ABC-NBD-21
ABC transporter ATP-binding protein - unknown substrate.
  
  
 
0.923
stpA
ABC transporter ATP-binding protein - unknown substrate; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
  
 
0.906
psaB
ABC transporter ATP-binding protein - manganese transport.
  
  
 
0.905
ABC-NBP
ABC transporter ATP-binding protein - unknown substrate; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
  
 
0.905
adcC
ABC transporter ATP-binding domain - Zinc (Zn2+) permease; Part of the ATP-driven transport system AdcABC for zinc. Required for transformability (By similarity).
     
0.900
spr0635
Hypothetical protein.
 
     0.813
spr1292
Conserved hypothetical protein.
 
 
 0.810
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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