Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ctpAP-type ATPase - probable copper transporter. (750 aa)    
Predicted Functional Partners:
spr0640
Conserved hypothetical protein.
 
   
0.861
copY
COPAB ATPases metal-fist type repressor.
  
  
 0.852
trxA
Thioredoxin reductase; Belongs to the thioredoxin family.
 
  
 0.613
spxB
Pyruvate oxidase; Belongs to the TPP enzyme family.
  
  
 0.590
pgk
Phosphoglycerate kinase.
 
    
 0.583
nusG
Transcription antitermination factor; Participates in transcription elongation, termination and antitermination.
      
 0.522
pacL
P-type ATPase - calcium transporter; Putative calcium transporter.
 
 
0.406
ribD
Riboflavin biosynthese; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.402
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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