Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0650Conserved hypothetical protein; Similar to mutator protein MutT; Belongs to the Nudix hydrolase family. (151 aa)    
Predicted Functional Partners:
spr0651
Conserved hypothetical protein.
       0.725
spr1951
Conserved hypothetical protein; Probable sugar hydrolase.
   
    0.692
cmk
Cytidylate kinase.
  
    0.616
spr0652
Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
       0.605
spr0225
Hypothetical protein.
   
    0.573
dinP
DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.495
clpE
ATP dependent protease; Belongs to the ClpA/ClpB family.
  
  
 0.463
spr0653
Conserved hypothetical protein; Probable transcriptional regulator.
  
    0.430
spr1411
Conserved hypothetical protein; Probable cation transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
    0.417
spr0073
Hypothetical protein.
   
    0.415
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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