spr0669 protein (Streptococcus pneumoniae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

spr0669

Hypothetical protein. (271 aa)

Predicted Functional Partners:

ptsG

0.992

malM

0.940

nplT

0.906

amy

0.906

spr0773

0.715

spr0785

0.609

spr0789

0.582

spr0786

0.556

spr0788

0.545

malP

0.529

Your Current Organism:

Streptococcus pneumoniae

NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
amy	malM	spr1239	spr1917	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	0.917
amy	malP	spr1239	spr1916	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.925
amy	nplT	spr1239	spr0948	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	0.906
amy	ptsG	spr1239	spr0668	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	PTS glucose-specific enzyme IIABC component.	0.551
amy	spr0669	spr1239	spr0669	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	Hypothetical protein.	0.906
malM	amy	spr1917	spr1239	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	0.917
malM	malP	spr1917	spr1916	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.999
malM	nplT	spr1917	spr0948	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	0.987
malM	ptsG	spr1917	spr0668	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	PTS glucose-specific enzyme IIABC component.	0.777
malM	spr0669	spr1917	spr0669	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	Hypothetical protein.	0.940
malP	amy	spr1916	spr1239	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	0.925
malP	malM	spr1916	spr1917	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	0.999
malP	nplT	spr1916	spr0948	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	0.962
malP	ptsG	spr1916	spr0668	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	PTS glucose-specific enzyme IIABC component.	0.460
malP	spr0669	spr1916	spr0669	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Hypothetical protein.	0.529
nplT	amy	spr0948	spr1239	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	Alpha-amylase precursor; Belongs to the glycosyl hydrolase 13 family.	0.906
nplT	malM	spr0948	spr1917	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	4-alpha-glucanotransferase (amylomaltase); Belongs to the disproportionating enzyme family.	0.987
nplT	malP	spr0948	spr1916	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.962
nplT	ptsG	spr0948	spr0668	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	PTS glucose-specific enzyme IIABC component.	0.551
nplT	spr0669	spr0948	spr0669	Neopullulanase; Belongs to the glycosyl hydrolase 13 family.	Hypothetical protein.	0.906

page 1 of 3

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About