Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spr0695Conserved hypothetical protein. (419 aa)    
Predicted Functional Partners:
spr0693
Conserved hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.999
ABC-NBD-11
ABC transporter ATP-binding protein - unknown substrate.
 
 0.999
ABC-NBD
ABC transporter ATP-binding protein - amino acid transport.
 
 0.963
ABC-NBD-28
ABC transporter ATP-binding protein - unknown substrate.
 
 0.943
ABC-NBD-14
ABC transporter ATP-binding protein - unknown substrate.
 
 0.940
ABC-NBD-27
ABC transporter ATP-binding protein - unknown substrate.
 
 0.927
ABC-NBD-7
ABC transporter ATP-binding protein - sodium transport.
 
 0.917
ftsE
ABC transporter ATP-binding protein & cell division protein; Part of the ABC transporter FtsEX involved in cellular division.
   
 0.904
ABC-NBD-23
ABC transporter ATP-binding protein - unknown substrate.
 
 
 0.897
ABC-NDB
ABC transporter ATP-binding protein - unknown substrate.
 
 0.888
Your Current Organism:
Streptococcus pneumoniae
NCBI taxonomy Id: 171101
Other names: S. pneumoniae R6, Streptococcus pneumoniae (strain ATCC BAA-255 / R6), Streptococcus pneumoniae R6, Streptococcus pneumoniae str. R6
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